-Preepitheliomatous keratosis.
· Bowen's disease - Queyrat erythroplakia: when surgery is not possible, this treatment can be used but healing should be monitored.
· Genital warts.
How to take it
Before any application, it is advisable to ensure the exact nature of the lesion to be treated: it may be necessary to perform a biopsy.
In principle, one to two applications per day in a thin layer and in small quantities, exclusively on the lesions.
Application to healthy skin should be avoided.
Treatment should be continued for several weeks (3 to 4 on average), under medical supervision.
When a lesion persists beyond the normal healing times, it will be necessary to perform a new biopsy.
In some cases, when a better penetration of the active substance is desired, the dermal cream will be applied with an occlusive dressing renewed every day.
The application of this medicament can be a useful preparation or a necessary complement to surgical curettage or by cryotherapy, chemotherapy, laser.
After application to a lesion, the therapeutic response can manifest itself in 4 stages:
1. simple or no inflammatory.
2. more severe inflammatory: erythema, burning, edema, vesicle.
3. destruction of the lesion with erosion, ulceration, necrosis.
4. re-epithelization then healing with possible hyperpigmentation.
This normal therapeutic response is not an adverse effect. Its particular importance in certain subjects, at stage 2 and 3, can lead to a temporary suspension of treatment or its adaptation: reducing the rate of applications, removing an occlusive dressing, using local treatments with emollients or even local corticosteroids.
Possible side effects
Pain at the point of application
Itching at the point of application
Burn at the point of application
Allergic skin reaction
Systemic toxicity
Erythematous reaction
Hematologic disorder
0 comments:
Post a Comment